Species differences in cardiovascular physiology that affect pharmacology and toxicology
نویسندگان
چکیده
منابع مشابه
Pharmacology and Toxicology of Leflunomide
Leflunomide (LEF), used for rheumatoid arthritis, inhibits dihydro-orotate dehydrogenase (DHODH) and tyrosine kinase (TK) enzymes and has anti-inflammatory, lymphocyte proliferation regulatory, immunosuppression and chondroprotective effects. The most common adverse effects are gastrointestinal disorders, weight loss, hypertension, skin infection, and neurological and hematological toxicity. It...
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leflunomide (lef), used for rheumatoid arthritis, inhibits dihydro-orotate dehydrogenase (dhodh) and tyrosine kinase (tk) enzymes and has anti-inflammatory, lymphocyte proliferation regulatory, immunosuppression and chondroprotective effects. the most common adverse effects are gastrointestinal disorders, weight loss, hypertension, skin infection, and neurological and hematological toxicity. it...
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ژورنال
عنوان ژورنال: Current Opinion in Toxicology
سال: 2020
ISSN: 2468-2020
DOI: 10.1016/j.cotox.2020.07.004